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KMID : 0352719940180030151
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Journal of Ginseng Research
1994 Volume.18 No. 3 p.151 ~ p.159
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An Experimental Study on the Effect of Immunopotential and the Anticancer Effect of Red Ginseng Extract.
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장성강
김주헌/정윤신/안동춘/강명재/이동근/김상호
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Abstract
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To evaluate the anticarcinogenic effect and its mechanism of red ginseng the, mice were treated with red ginseng and received subcutaneous B16 melanoma cell line injection on the back. Tumor incidence was same (100%) both in water and red
ginseng-treated groups, but tumor production was delayed in red ginseng-treated group. Survival time was somewhat longer in red ginseng-treated group. The histopathological findings were similar in both groups. but lymphocytic infiltration around
the
tumor and melanin production in the tumor cells were prominent in the red ginseng-treated group. Flow cytometric analysis on T lymphocytes and natural killer cells revealed increased TH/TS ratio and increased NK cells in red ginseng-treated
group.
These
results suggest that the anticarcinogenic effect of red ginseng may be exerted by the increased cell-mediated immunity and natural killer cell activity.
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KEYWORD
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